Full Description                 STUDIE IS GESLOTEN

Randomized phase III Trial comparing concurrent chemoradiation and adjuvant chemotherapy with pelvic radiation alone in high risk and advanced stage endometrial carcinoma: PORTEC 3 Date activated: 2006 Randomised: Yes Quality of life: yes

Dutch title Gerandomiseerde fase III studie waarbij de toevoeging van chemotherapie tijdens en na uitwendige radiotherapie vergeleken wordt met radiotherapie alleen bij patienten met hoog risico of gevorderd stadium enometrium carcinoom: PORTEC 3 Disciplines: gyn/medical oncology/radiotherapy.

Funding: KWF-CKTO

PORTEC website

 

 Co├Ârdinator

Dr. C. L. Creutzberg, radiation oncologist, Leiden University Medical Cente
Dr. H. Nijman, gynaecological oncologist, UMC Groningen
Dr. R. Kruitwagen, gynaecological oncologist, MUMC, Maastricht 
Dr. P.B. Ottevanger, medical oncologist, UMC Radboud, Nijmegen

Treatment arms:

Pelvic radiation combined with concurrent and adjuvant chemotherapy vs pelvic radiation alone Categories: endometrial cancer Phase: III
Number of patients: 500 (800 if average no of patients per year > 100)
planned duration: 5 years or recruitment